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American Society of Hypertension Nationally Designated Hypertension Practice Center

Jonathan J.Lebowitz, M.D

Education:

Undergraduate College: Columbia College of Columbia University, A.B: Psychology

Medical School: State University of New York Health Science Center at Brooklyn

Residency: Internal Medicine, University of Pittsburgh Medical Center

Nephrology Fellowship: University of Pittsburgh Medical Center

Certifications:

Board Certified in Internal Medicine by the American Board of Internal Medicine 1998

Board Certified in Nephrology by the American Board of Internal Medicine 2000

Academic Appointments:

Director - Nephrology Fellowship, Division of Nephrology, Department of Medicine, Robert Wood Johnson Medical School, (April 2016 - 2022)

Associate Director - Nephrology Fellowship, Division of Nephrology, Department of Medicine, Robert Wood Johnson Medical School, (October 2013-March 2016)

Associate Professor of Medicine - Division of Nephrology, Department of Medicine, Robert Wood Johnson Medical School (May 2008-Present)

Associate Director - Nephrology Fellowship, Renal Electrolyte Division, Department of Medicine, University of Pittsburgh Medical Center (June 2004-May 2008)

Director of Renal Outpatient Clinics - Renal Electrolyte Division, Department of Medicine, University of Pittsburgh Medical Center (July 2003-May 2008)

Assistant Professor of Medicine - Renal Electrolyte Division, Department of Medicine, University of Pittsburgh Medical Center (July 2001-May 2008)

Clinical Instructor - Renal Electrolyte Division, Department of Medicine, University of Pittsburgh Medical Center (July 2000-June 2001)

Non-Academic Appointments:

Research Assistant: Renal Division, College of Physicians and Surgeons, Columbia University, New York, NY

RESEARCH/FUNDING

Primary Investigator: FGCL-4592-060; A Phase 3, Randomized, Double-Blind, Placebo Controlled Study of the Efficacy and Safety of Roxadusta! (FG-4592) for the Treatment of Anemia in Chronic Kidney Disease Patients not on Dialysis. 2015-2017.

Co-investigator: A Phase 3, Open-Label, Multicenter, Prospective, Randomized Study of the Efficacy and Safety of conversion from Prograf Capsules Twice Daily to LCP-Tacro Tablets Once Daily for the Prevention of Acute Allograft Rejection in Stable Kidney Transplant Patients. 2008-2011.

Co-investigator: Neurotransplantation for patients with subcortical motor stroke: a phase 2, randomized trial with BS-Neurons; Layton BioScience, Inc., at the University of Pittsburgh, 2002-2004.

1 K08 DK067143-01, DDK-D, Kinase Regulation of the Epithelial Sodium Channel, 2004-2008.

1 F32 DK010164, DDK, Rate of Na+ Entry Determines Chronic Adaptation of ENaC, 2001-2004.

Selected Publications

Refereed Original Article in Journal

Edwards JC, van Adelsberg J, Rater M, Herzlinger D, Lebowitz, J, al-Awqati Q. Conditional immortalization of bicarbonate-secreting intercalated cells from rabbit.
Am J Physiol (263):C521-9, 1992.

Banerji MA, Lebowitz J, Chaiken RL, Gordon D, Kral JG, Lebovitz HE. Relationship of visceral adipose tissue and glucose disposal is independent of sex in black NIDDM subjects.
Am J Physiol (273): E425-432, 1997.

Lebowitz J, An B, Edinger B, Zeidel M, Johnson JP. Effect of Altered Na+ entry on expression of apical and basolateral transport proteins, Am J Physiol, 2003.

Lebowitz J, Edinger B, An B, Perry CJ, Onate S, Kleyman TR, Johnson JP. IKKbela modulation of ENaC activity, J Biol Chem, July 28, 2004.

Kondziolka D, Steinberg GK, Wechsler L, Melter CC, Elder E, Gebel J, Decesare, S, Jovin T, Zafonte R, Lebowitz J, Flickinger JC, Tong D, Marks MP, Jamieson C, Neurotransplantation for for patients with subcortical motor stroke, a phase 2 randomized trial,
J Neurosurg. 2005 Jul; | 03(1):38-45.

Hill WG, Butterworth MB, Wang H, Edinger RS, Lebowitz J, Peters KW, Frizzel RA,Johnson JP, The epithelial sodium channel (ENaC) traffics to apical membrane in lipid rafts in mouse cortical collecting duct cells, J Biol Chem, October 10, 2007.

Mann DM, Fyfe B, Osband AJ, Lebowitz J, Laskow DA, Jones J, Mann RA. Sarcoidosis within a renal allograft: a case report and review of the literature. Transplant Proc. 2013 Mar;45(2):838-41.

Pieloch D, Dombrovskiy V, Osband AJ, Lebowitz J, Laskow DA, Morbid obesity is notan independent predictor of graft failure or patient mortality after kidney transplantation, J Ren Nutr. 2014 Jan;24(1):50-7. doi: 10.1053/jjrn.2013.07.001. Epub 2013 Sep 23.

Mann DM, Fernandez S, Mondal 2, Laskow D, Osband A, Debroy M, Lebowitz J, CoromilaJ, Vagaonescu T, Moreyra A, Melita EA, Mann RA. Role of Coronary Angiography in the Assessment of Cardiovascular Risk in Kidney Transplant Candidates. Am J Cardiol. 2016 Sep 1:118(5):679-83. doi: 10.1016/jamjcard.2016.06.017. Epub 2016 Jun i5. PubMed PMiD: 27392506.

Lederer E, Lebowitz J, Current State of the Workforce in Nephrology, Adv Chronic Kidney Dis. 2020 Jul;27(4):281-290.el. doi: 10.1053/jackd.2020.07.007. Epub 2020 Oct


Other Articles (Reviews, Editorials, etc.) In Journals; Chapters; Books; other Professional Communications

Lebowitz J. Is academic medicine for sale? Letter to the editor, N Engl J med. 2000 Aug 17:343(7); 509.

Planninsic R and Lebowitz J. Renal Failure in End-stage Liver Discase and Liver Transplantation, International Anesthesiology Clinics. 44(3):35-49, June 2006. Abstracts

[A0159] Hug MJ, Lebowitz J, Frizzell R, Johnson JP. Whole Cell Properties of A6 Cells Grown on Collagen Membranes: Effects of Forskolin and Amiloride; Abstract, ASN Renal Week 1999.

[A0164] Lebowitz J, Johnson JP; Renal/Medicine. Sodium channel (ENaC) subunits are present in lipid rafts in A6 cells. Hill WG, An B, Abstract, ASN Renal Week 200

[SA-FC045] Lebowitz J, Edinger R, Ramkumar M, Onate S, Kleyman TR, Johnson JP. A novel kinase interacts with and augments ENaC function, Abstract/presentation, ASN Renal Week. 2003.

[SA-FC045] Lebowitz J, C. Perry, Edinger, Kleyman TR, JP Johnson. IKKß regulates ENC surface expression and activity in oocytes, Abstract/Presentation, AN Renal Week, 2004.

[P00295] Sharma P, Lebowitz J, Patient with Refractory Acquired Thrombotic Thrombocytopenic Purpura Treated with a Novel Agent Caplacizumah. Abstract, ASN, Kidney Week, 2021.

[P01493] Sharma P, Khalil S1, Lebowitz J, Nephrotic Range Proteinuria due to ANCA - Associated Vasculitis in a Diffuse Systemic Sclerosis Patient: A Rare Presentation, Abstract, ASN Kidney Week, 2021.

[PUB|17] Patnaik P, Sharma P, Khalil SI, Lebowitz J, Atraumatic Splenic Rupture in a Patient on Apixaban and Clopidogrel, Abstract, AS Kidney Weck, 2021.